Minimal Deviation Endometrioid Adenocarcinoma of the Uterine Cervix - A Case Report

first described by Gusserow in 1870 as a well differentiated adenocarcinoma in which most of the glands are impossible to be distinguished from the normal endocervical mucosa, although the MDA invades deep into the cervical stroma. At first, MDA was restricted to the mucinous type, but the definition of MDA has been expanded to other cell types, including the endometrioid, clear cell and nonspecific cellular types of differentiation. Minimal deviation endometrioid adenocarcinoma (MDEA) is a variant of MDA, and it is characterized by the proliferation of infiltrative, mildly atypical endometrioid glands with no or minimal stromal reaction. Only 17 cases of cervical MDEA have been reported in the English literature. In this current report, we describe our recent experience of a patient with MDEA and we compare this case with the previous reports.